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Rezulin® (troglitazone)

Rezulin (troglitazone) is in a class of anti-diabetic drugs called “thiazolidinediones” that are used in the treatment of type II diabetes. Patients with type II diabetes cannot make enough insulin, and the cells of their body do not respond normally to the reduced amounts of insulin that are present. Rezulin is often referred to as an “insulin sensitizer” because it attaches to the insulin receptors on cells throughout the body and causes the cells to become more sensitive (more responsive) to insulin. As a result, more glucose is removed from the blood.

Why is Rezulin prescribed?

Rezulin is prescribed to reduce the amount of glucose (sugar) in the blood. In addition, Rezulin may alter the blood concentrations of lipids (fats) in the blood by decreasing triglycerides and increasing the “good” (HDL) cholesterol.

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What are the FDA approved uses for Rezulin?

Rezulin was approved by the FDA in 1999 for the treatment of type II diabetes.

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What are the side effects of Rezulin?

The most common side effects associated with Rezulin are upper respiratory tract infection, headache, sinusitis, muscle aches, tooth disorders, hypoglycemia, and sore throat.

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Rezulin warnings and alerts

Rezulin was recalled on March 21, 2000 after a controversial FDA approval and stay on the U.S. market. There have been an estimated 430 Rezulin patients that suffered liver failure, including 391 deaths. It was found that a Rezulin patient’s risk of liver failure was increased 1,200 times by taking the drug.

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Rezulin drug contradictions

Rezulin is contraindicated in patients with renal failure and/or a history of liver problems.

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Rezulin FAQs

Liver Failure Symptoms: Are You Experiencing Liver Failure?

Symptoms of liver failure include jaundice, sever fatigue, abdominal pain, weight loss, nausea, loss of appetite, back pain, darkened urine, and vomiting.

What is a liver transplantation operation?

A liver transplant operation replaces a diseased or failed liver with a new one or a portion of one from a donor. Rezulin patients who have experienced liver failure have needed to have liver transplants.

When did Warner-Lambert first learn of the serious Rezulin side effects?

Rezulin manufacturer Warner-Lambert has been accused of knowing as early as 1993 of at least 12 people who had suffered potentially life-threatening liver damage during Rezulin’s clinical trials. Further, in the first 18 months Rezulin was on the market, there were 56 reports from FDA records showing heart failure.

I understand why I need to see a doctor immediately, but why do I need a lawyer right away?

Your claim is subject to one of more state or federal statutes of limitations. These are laws limiting the time in which a lawsuit must be filed, and they vary from state to state and between state and federal law. If your claim is not already settled, or a lawsuit filed on your behalf within the time frame set by the statute, you will be barred from receiving any financial or other compensation, no matter how serious your injury or how strong your claim. For more information, contact an experienced defective drug litigation attorney today to discuss your legal options.

Can I file a lawsuit if I have suffered damages from taking Rezulin?

Possibly. While all medications have certain, anticipated side effects, a drug manufacturer has a duty to inform physicians adequately regarding the known risks associated with its drugs. If a manufacturer fails to do so, it can be held responsible to patients who are injured as the result of inadequate warnings, under a legal theory known as “product liability.” Depending upon the particular circumstances of your case, damages may include recovery for any of the following:

  • Past and future medical expenses
  • Past and future pain and suffering
  • Lost wages
  • Loss of future earning capacity
  • Emotional distress

If you or a loved one has experienced any health problems while taking Rezulin, you should contact your doctor immediately. You may also wish to contact an experienced Rezulin lawyer to discuss your legal options. As all legal claims are subject to time limits, however, you may risk forfeiture of your right to financial compensation if you delay.

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