Yes. These conditions, and potential side effects, include:
Allergic reactions to Celebrex. People with allergies to Sulfonamides (sulfadiazine, sulfisoxazole, Gantanol, or Thiosulfil), other NSAIDs, carry a much higher risk of an allergic reaction to Celebrex.
Anemia – Celebrex may trigger this condition in rare cases, and should be used cautiously by individuals with a prior history of this iron deficiency.
Asthma – Celebrex could trigger an asthma attack. Asthmatics that are sensitive to Aspirin are at the highest risk for an allergic reaction to Celebrex.
Dehydration – Due to the increased risk of kidney damage, people suffering from dehydration should not take Celebrex.
Diabetics – are especially vulnerable to side effects, and should not take Celebrex.
Heart problems – Long-term Celebrex treatment may cause renal toxicity and decreased blood flow to the heart. Patients with pre-existing heart conditions, liver problems, and those taking diuretics or angiotensin converting enzyme (ACE) inhibitors are most likely to be affected. High blood pressure is also a possible side effect of Celebrex.
Kidney or liver impairment – Celebrex could aggravate or trigger these conditions. Kidney damage may also result from long-term use of Celebrex.
Pregnancy – COX-2 inhibitors like Celebrex should not be taken in the last 3 months of pregnancy, and have not been studied for safety earlier in pregnancy.
Ulcer or Gastrointestinal (GI) Bleeding – Celebrex may cause or aggravate deterioration and bleeding in the GI tract.